Dr. Guyatt is a world leader in evidence-based medicine, a term that first appeared in a paper he published in 1992. He is widely known for his teaching, mentoring and advocacy. Dr. Guyatt’s contribution to quality of life research, randomized trials and meta-analysis have been considered groundbreaking. He is the co-editor of the Users’ Guides to the Medical Literature, a comprehensive set of journal articles and textbook for clinicians who wish to incorporate evidence-based medicine into their practices. He has published more than 450 peer-reviewed articles in medical journals, and has also written extensively on health care policy in the popular press. In 1979, Dr. Guyatt co-founded the Medical Reform Group, a Canadian organization of physicians, medical students and others in support of universal public health care. He continues to serve as a member of the steering committee and leading spokesperson for this group.